Trials / Unknown
UnknownNCT04038554
Microbiota in Acute Pancreatitis: Prospective Multicenter Study
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 168 (estimated)
- Sponsor
- Corporacion Parc Tauli · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The objective of the study is to classify and carry out a quantitative analysis of the different bacterial species present in the intestinal microbiota of patients with acute pancreatitis and determine if there are significant differences regarding healthy controls. At the same time, the investigators pretend to determine if there are differences according to the etiology and severity of the disease and if the disregulation is temporary or is maintained after one month of discharge. To carry out this purpose, the investigators have designed a prospective and multicentre observational study where samples of feces and saliva of patients admitted for acute pancreatitis of different etiologies and severity will be analyzed.
Detailed description
The study of the human microbiota is gaining importance given its relationship with the homeostasis of the organism as well as with certain pathologies. Specifically in the case of acute and chronic pancreatitis, recent studies suggest the disregulation of the intestinal flora as a possible determinant in the development and evolution of the disease. If this hypothesis is confirmed, hygienic-dietetic measures, as well as the administration of antibiotics, probiotics or fecal transplantation, may have therapeutic implications. The objective of the study is to classify and carry out a quantitative analysis of the different bacterial species present in the intestinal microbiota of patients with acute pancreatitis and determine if there are significant differences regarding healthy controls. At the same time, the investigators also intend to determine if there are differences according to the etiology and severity of the disease and if the disregulation is temporary or is maintained after one month of discharge. To carry out this purpose, it has been designed a prospective and multicentre observational study where samples of feces and saliva of patients admitted for acute pancreatitis of different etiologies and severity will be analyzed .
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Feces and saliva analysis | Qualitative and quantitative analysis of the microbiota in the feces and saliva by mRNA sequencing. |
Timeline
- Start date
- 2020-05-01
- Primary completion
- 2020-09-01
- Completion
- 2020-09-01
- First posted
- 2019-07-31
- Last updated
- 2020-03-18
Locations
2 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT04038554. Inclusion in this directory is not an endorsement.