Trials / Completed
CompletedNCT04036929
Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis?
Hand Osteoarthritis: Investigating Pain Effects in a Randomised Placebo-controlled Feasibility Study of an Estrogen-containing Therapy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 28 (actual)
- Sponsor
- University of Oxford · Academic / Other
- Sex
- Female
- Age
- 40 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Post-menopausal women aged 40-65 with symptomatic hand osteoarthritis are invited to take part in this feasibility study. The study's aim is to investigate whether it is acceptable to women with painful hand OA to take an estrogen-containing therapy, and what is the best way of collecting some of the information in order to facilitate planning a full size trial. The investigator's long-term aim is to find out whether giving estrogen-containing therapy to women after the menopause improves hand OA symptoms.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Estrogen-bazedoxifene | Conjugated estrogens 0.45 mg-bazedoxifene acetate 20 mg. |
| DRUG | Placebo oral tablet | Placebo oral tablet |
Timeline
- Start date
- 2019-05-09
- Primary completion
- 2021-08-19
- Completion
- 2021-12-10
- First posted
- 2019-07-30
- Last updated
- 2022-04-21
Locations
3 sites across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT04036929. Inclusion in this directory is not an endorsement.