NCT04035174

Evaluation of the Diagnosis Performances of DEC LTS-2 Skin Patch for Onchocerciasis in Central Africa

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Center for Research on Filariasis and Other Tropical Diseases, Cameroon · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study aims at evaluating the diagnosis performances of the LTS-2 DEC patch for onchocerciasis compared to the gold standard which are the skin snips. This study will be conducted in Cameroon in two different areas : Ngog-Mapubi and Bafia Health Districts (one area only endemic for onchocerciasis, and one area endemic for both loiasis and onchocerciasis).

Conditions

• Onchocerciasis
• Loiasis
• Diagnoses Disease
• Neglected Diseases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	LTS-2 DEC patch	After 24 hours, the patch will be removed, and then the reaction of the skin under the device will be assessed : no reaction, weak reaction (\< 50% skin surface under the patch), medium reaction (\> 50% skin surface under the patch), and important reaction (reaction on all the surface of the skin under the patch).
DIAGNOSTIC_TEST	Skin snips	Regarding skin snips, a reading will be done at 24 hours after incubation of the skin in saline serum during 24 hours.

Timeline

• Start date: 2022-09-01
• Primary completion: 2022-10-30
• Completion: 2023-03-30
• First posted: 2019-07-29
• Last updated: 2025-03-25

Locations

1 site across 1 country: Cameroon