NCT04033458

A Study of JNJ-64140284 Solid Dose Formulations in Healthy Male Participants

A Randomized, Open-Label, 5-way Crossover Study in Healthy Male Participants to Evaluate the Bioavailability, Food Effect, Safety and Tolerability of Two Oral Solid Dosage Formulations Relative to an Oral Solution Formulation of JNJ-64140284.

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: Janssen Research & Development, LLC · Industry
• Sex: Male
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare the pharmacokinetic profile of a single dose of two solid dosage formulations relative to a reference formulation (solution in polyethylene glycol-400 \[PEG-400\]) of JNJ-64140284 in healthy male participants under fasting condition and to assess the effect of food on the bioavailability of two solid dosage formulations of JNJ-64140284.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	JNJ-64140284	Participants will receive JNJ-64140284 orally.

Timeline

• Start date: 2019-07-29
• Primary completion: 2019-08-01
• Completion: 2019-08-01
• First posted: 2019-07-26
• Last updated: 2025-04-27

Locations

1 site across 1 country: Belgium