NCT04032210

The Influence of Preventive Regimens Containing Different Toothpastes on Caries Risk of High Risk Patients: A Randomized Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

66 Participants will be divided into three groups according to the tested regimen (A), where (A1) represents participants will be exposed to regimen including dual zinc plus arginine based toothpaste (Colgate total), (A2) represents participants will be exposed to regimen including zinc based toothpaste (Crest complete) and (A3) represents control group where participants will be used fluoride based toothpaste (Signal). The study will be carried over a period of one year, assessment of cariogram will be done in two visits: first visit (baseline: T0) and second visit (after 3 months: T3) . In addition assessment of DMF scores will be done in four visits: first visit (baseline: T0), second visit (after 3 months: T3), third visit (after 6 months: T6) and final visit (after 12 months: T12) to obtain the required data

Conditions

• Prevention of Dental Caries

Interventions

Type	Name	Description
OTHER	dual Zinc plus Arginine based toothpaste (Colgate total)	Regimen using dual Zinc plus Arginine based toothpaste (Colgate total)
OTHER	Zinc based toothpaste (Crest complete)	Regimen using Zinc based toothpaste (Crest complete)
OTHER	Fluoride based toothpaste (Signal)	Fluoride based toothpaste (Signal)

Timeline

• Start date: 2019-10-01
• Primary completion: 2020-10-01
• Completion: 2020-11-01
• First posted: 2019-07-25
• Last updated: 2019-07-26

Locations

1 site across 1 country: Egypt