NCT04030520

Improving Uptake and Adherence to HIV Prevention Services With Pre-exposure Prophylaxis (PrEP), HIV Self- Testing and Adherence Support for Very High Risk HIV-negative Young Women Aged 15-24 in Kampala, Uganda

Improving Uptake and Adherence to HIV Prevention Services With PrEP, HIV Self- Testing and Adherence Support for Very High Risk HIV-negative Young Women Aged 15-24 in Kampala, Uganda

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: Female
• Age: 15 Years – 24 Years
• Healthy volunteers: Accepted

Summary

The main aim is to develop and assess an intervention to enhance initiation and adherence to PrEP among HIV negative young women of high risk (YWHR). The specific aims are (1) To conduct formative research to enhance our understanding of the dynamics of the social and sexual networks, and context of young HIV-uninfected women (aged 15-24) engaged in high risk sexual behavior in Kampala, Uganda (2) Document barriers and opportunities for PrEP uptake and adherence as well as repeat HIV testing by self test; (3) To develop and test a socially and culturally acceptable and feasible prevention intervention on uptake and adherence to PrEP and HIV self-testing for young women at high risk for HIV.

Conditions

• HIV/AIDS

Interventions

Type	Name	Description
BEHAVIORAL	POPPi	behavioral intervention with offer of HIV self test
BEHAVIORAL	Comparison	standard of care

Timeline

• Start date: 2019-07-08
• Primary completion: 2020-10-31
• Completion: 2021-10-31
• First posted: 2019-07-24
• Last updated: 2025-07-15
• Results posted: 2025-07-15

Locations

1 site across 1 country: Uganda