Trials / Completed
CompletedNCT04030286
Evaluation of Malondialdehyde in Periodontal and Cardiovascular Disease
Analysis of Serum and Salivary Malondialdehyde and Lipid Profile Levels in Patients With Periodontal and Cardiovascular Diseases
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 133 (actual)
- Sponsor
- University of Messina · Academic / Other
- Sex
- All
- Age
- 20 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
Malondialdehyde (MDA) plays a key role in endothelial function and may be a link for the known interaction of periodontitis and coronary heart disease (CHD). The investigators compared the impact of gingival health, periodontitis (CP), CHD or of both diseases (CP+CHD) on saliva and serum MDA levels.
Detailed description
The aim of this study was to evaluate a possible association between both saliva and serum MDA levels in patients with CP and with CHD and if the serum MDA levels are mediated by serum CRP
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observation | Evaluation of Malondialdehyde level and correlation of Malondialdehyde level with periodontal and cardiovascular disease |
Timeline
- Start date
- 2014-01-03
- Primary completion
- 2018-09-09
- Completion
- 2019-04-01
- First posted
- 2019-07-23
- Last updated
- 2019-07-23
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT04030286. Inclusion in this directory is not an endorsement.