NCT04029792

Evaluation of a Combination of Plant Extracts (BSL_EP028) on Joint Mobility

Pilot Study to Evaluate the Effect of the Consumption of the Combination of Plant Extracts (BSL_EP028) on Joint Mobility, Physical Performance and Vitality

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Biosearch S.A. · Industry
• Sex: All
• Age: 55 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The aim of this trial is to study the effect of the combination of plant extracts (BSL\_EP028) on joint mobility, physical performance and vitality in a group of healthy older adults who remit some joint discomfort. This is a preliminary study whose purpose is to gather information for future studies.

Detailed description

The natural aging process involves several body changes that can affect to the mobility of subjects. Among them, those that affect the joints may have the greatest impact on mobility. With age, there is a progressive loss of the cartilage that covers the joints, as well as the synovial fluid, which in turn increases the stiffness of the ligaments and tendons that allow joint mobility, which implies a reduction in muscle tone and bone strength. This joint degeneration produces pain and discomfort, which leads to stiffness and restriction of movement. Therefore, and as a consequence of this loss of mobility, subjects decrease their physical performance, which can affect their mood and vitality. All of these may lead to a loss of quality of life and to an increase of the risk of future adverse health events, such as disability, institutionalization, hospitalization and the need for home medical care. For all these reasons, and considering the increase in the ageing population worldwide, it seems relevant to develop new strategies to improve joint mobility, physical performance and vitality that are safe for the consumer, affordable and not associated with undesirable side effects. In this regard, natural plant extracts have been widely used as a traditional remedy to reduce joint pain, reduce fatigue and improve mood and physical performance.

Conditions

• Joint Diseases

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Combination of plant extracts (BSL_EP028)	Each participant will consume 2 capsules daily, in the morning and at night without any restriction in the diet nor in their habits of life.
COMBINATION_PRODUCT	Placebo	Each participant will consume 2 capsules daily, in the morning and at night without any restriction in the diet nor in their habits of life.

Timeline

• Start date: 2019-10-15
• Primary completion: 2020-10-15
• Completion: 2020-10-15
• First posted: 2019-07-23
• Last updated: 2020-05-13

Locations

1 site across 1 country: Spain