Clinical Trials Directory

Trials / Completed

CompletedNCT04028349

ZEBOVAC (Ebola Vaccine Trial, Ad26.ZEBOV/MVA-BN-Filo)

An Open-label, Single Arm Study to Provide Additional Information on Immunogenicity and Safety of Ad26.ZEBOV/MVA-BN-Filo

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
800 (actual)
Sponsor
MRC/UVRI and LSHTM Uganda Research Unit · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

An open-label, single arm phase II study of the candidate Ebola Vaccine Ad26.ZEBOV/MVA-BN®-Filo

Detailed description

This is an interventional, single arm, open-label, non-randomized, phase II study to accumulate additional data on immunogenicity and safety of Ad26.ZEBOV/MVA-BN®-Filo against Ebola virus disease. It also has a qualitative component to better understand knowledge about Ebola virus disease and the perception and attitudes towards the vaccine amongst participants (Healthcare and Frontline workers).

Conditions

Interventions

TypeNameDescription
DRUGAd26.ZEBOV/MVA-BN-FiloCandidate Ebola Vaccine

Timeline

Start date
2019-08-01
Primary completion
2021-03-19
Completion
2021-03-19
First posted
2019-07-22
Last updated
2021-05-12

Locations

1 site across 1 country: Uganda

Source: ClinicalTrials.gov record NCT04028349. Inclusion in this directory is not an endorsement.