NCT04027738

a Single Intraarticular Injection of PRP for Early Knee OA

Efficacy of a Single Intraarticular Injection of Platelet-Rich Plasma for the Treatment of Early Knee Osteoarthritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Kaohsiung Veterans General Hospital. · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to investigate the efficacy of a single intraarticular injection of PRP for the treatment of early knee OA.

Detailed description

Platelet-rich plasma (PRP) has been reported to be effective for the treatment of knee osteoarthritis (OA). This study aimed to investigate the efficacy of a single intraarticular injection of PRP for the treatment of early knee OA. In a prospective trial with 6-month follow-up, patients with early knee OA were recruited and received a single intraarticular PRP injection. Several outcomes were measured.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
OTHER	PRP	The patients received a single 3-ml injection of PRP. Approximately 10-mL of venous blood was drawn from each patient and centrifuged using an Arthrex autologous conditioned plasma (ACP) kit (a low-leukocyte ACP system), spun at a speed of 1500 rpm for 5 minutes. The platelet concentration obtained was approximately 2-3 times greater than the baseline platelet concentration.

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-12-30
• Completion: 2017-12-30
• First posted: 2019-07-22
• Last updated: 2019-07-22

Locations

1 site across 1 country: Taiwan