NCT04024410

Optimal Positive End-expiratory Pressure (PEEP) in Prone Position During Spine Surgery

Optimal Positive End-expiratory Pressure (PEEP) in Prone Position During Spine Surgery. A Prospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Parc de Salut Mar · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Background: There is a lack of studies regarding Optimal (best) positive end-expiratory pressure (PEEP) in prone position during surgery, and its relation with optimal PEEP in supine position. Hypothesis: In patients undergoing scheduled spinal surgery, optimal PEEP in the prone position is lower than optimal PEEP in the supine position. Aims: To assess the difference optimal PEEP in supine vs. prone positions in patients undergoing spine surgery. To evaluate the changes in optimal PEEP in prone position throughout the surgical procedure. Methods: Observational study, one center. Main variable: optimal PEEP. Secondary variables: PaO2, pCO2 and dynamic compliance (Crd) in prone and supine position.

Detailed description

Recruitment: Patients scheduled for spine surgery were Main outcome: Optimal PEEP determined after a pulmonary recruitment manoeuvre in supine and in prone position and every hour during the surgery in prone position. Secondary outcomes: Pulmonary compliance, blood gas analysis and hemodynamic parameters

Conditions

• Anesthesia
• Surgery

Interventions

Type	Name	Description
OTHER	Evaluation of PEEP in prone position	Assessment of optimal Positive End-Expiratory Pressure (PEEP) in patients undergoing scheduled spine surgery in prone position.

Timeline

• Start date: 2019-06-03
• Primary completion: 2021-02-22
• Completion: 2021-02-22
• First posted: 2019-07-18
• Last updated: 2021-10-13

Locations

1 site across 1 country: Spain