NCT04021524

BPO vs Hibiclens Soap for Surgical Preparation

Randomized Trial of Hibiclens vs Benzoyl Peroxide Soap for Surgical Preparation

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: Male
• Age: 18 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized trial of benzoyl peroxide soap versus Hibiclens soap for surgical preparation. The objective is to determine whether benzoyl peroxide soap, commonly available in drug stores for over-the-counter acne treatment, is as or more effective than the standard surgical preoperative soap, Hibiclens soap (chlorhexidine gluconate), in reducing loads of Propionibacteria (Propi) on or under the skin of patients prior to shoulder arthroplasty (joint replacement).

Conditions

• Propionibacterium Acnes

Interventions

Type	Name	Description
DRUG	Benzoyl Peroxide 10% Bar	Patients will wash with Benzoyl Peroxide 10% Bar
DRUG	Chlorhexidine Gluconate	Patients will wash with Chlorhexidine Gluconate

Timeline

• Start date: 2018-09-10
• Primary completion: 2019-05-31
• Completion: 2021-04-16
• First posted: 2019-07-16
• Last updated: 2022-03-15
• Results posted: 2022-03-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study