NCT04018963

The Impact of Endoscopic Pituitary Surgery on Nasal Function

Numerical Simulation Analysis of Nasal Physiology After Endoscopic Pituitary Surgery.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Zhebao Wu · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to determine the impact of endoscopic transsphenoidal pituitary surgery on nasal function using a numerical simulation and to compare the difference between two kinds of transsphenoidal approachese(single nostril approach and bilateral nostril approach)．

Detailed description

Neuroendoscopic surgery is the first treatment for most pituitary adenoma patients. Because transsphenoidal surgery exploits the nasal corridor and paranasal sinuses to reach the skull base, sinonasal trauma is a primary source of postoperative morbidity in many of these patients. The aim of this study is to determine the impact of endoscopic transsphenoidal pituitary surgery on nasal function using a numerical simulation and to compare the difference between two kinds of transsphenoidal approachese(single nostril approach and bilateral nostril approach)．

Conditions

• Pituitary Tumor
• Endoscopic Surgery
• Quality of Life
• Function of Nose

Interventions

Type	Name	Description
PROCEDURE	Single nostril approach endoscopic transsphenoidal pituitary surgery	Single nostril approach endoscopic transsphenoidal pituitary surgery
PROCEDURE	Bilateral nostril approach endoscopic transsphenoidal pituitary surgery	Bilateral nostril approach endoscopic transsphenoidal pituitary surgery

Timeline

• Start date: 2019-07-25
• Primary completion: 2021-12-31
• Completion: 2021-12-31
• First posted: 2019-07-15
• Last updated: 2020-10-09

Locations

1 site across 1 country: China