Clinical Trials Directory

Trials / Completed

CompletedNCT04018599

Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS

A Phase I, Randomized, Open-label, Parallel-group Study to Determine the Pharmacokinetics, Safety, and Tolerability of MSB11022 (Proposed Adalimumab Biosimilar) Following a Single Subcutaneous Injection by an Auto-injector or by a Pre-filled Syringe in Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
216 (actual)
Sponsor
Fresenius Kabi SwissBioSim GmbH · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study is to demonstrate equivalence of the pharmacokinetic (PK) profile of MSB11022 administered by either an auto-injector (AI) or a pre-filled syringe (PFS) as single subcutaneous (s.c.) injection of 40 mg.

Conditions

Interventions

TypeNameDescription
DRUG40 mg MSB11022Single dose, as a solution, administered subcutaneously, using an auto-injector.
DRUG40 mg MSB11022Single dose, as a solution, administered subcutaneously, using a pre-filled syringe.

Timeline

Start date
2019-07-15
Primary completion
2020-03-17
Completion
2020-03-17
First posted
2019-07-12
Last updated
2020-03-25

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04018599. Inclusion in this directory is not an endorsement.