NCT04017728

Percutaneous Vertebroplasty Using Rotary Cutter for Bone Metastases

Percutaneous Vertebroplasty Using Rotary Cutter for Treating Bone Metastases

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Li Min · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Percutaneous vertebroplasty has been applied widely to treat bone metastases. The injected cement may strengthen the affected bone to prevent pathological fractures and relieve the pain. Moreover, the thermal reaction (70°C) due to polymerisation of cement also contributes to tumour destruction. The cement dose and diffusion pattern may be significant factors for the treatment efficacy, which can be affected by the inner pressure of the metastases. The investigators will apply a rotary cutter to destroy the structure of metastases to alleviate the pressure in the metastases. Then, more cement will be injected, which may effectively interdigitates with the surrounding bone and generate more thermo to kill the tumor cells.

Conditions

• Metastasis

Interventions

Type	Name	Description
DEVICE	Conventional Percutaneous Vertebroplasty	The cement is injected into the bone metastases directly.
DEVICE	Percutaneous Vertebroplasty with Rotary Cutter	The rotary cutter is applied before the cement injection. Then, the cement is injected with lower pressure.

Timeline

• Start date: 2019-07-30
• Primary completion: 2024-04-01
• Completion: 2025-12-01
• First posted: 2019-07-12
• Last updated: 2019-07-16

Locations

1 site across 1 country: China