NCT04016597

Nitric Oxide Lung Diffusing Capacity in Healthy, Non-smoking Adults

Comparison of Two Commercially Available Devices to Measure Nitric Oxide Lung Diffusing Capacity in Healthy, Non-smoking Adults

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 35 (actual)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The measurement of nitric oxide lung diffusing capacity (DLNO) has been recently standardised. To date, two pulmonary function devices are commercially available and are used for the measurement of DLNO. No previous study assessed differences in gas exchange outcomes (e.g., DLNO values) between both devices. The aim of this project is to compare two commercially available devices that measure lung diffusing capacity for nitric oxide (DLNO). 1. "MasterScreenTM" (PFT Pro, Jaeger, CareFusion, Hoechberg, Germany 2. "HypAir" ("HA", Medisoft, Dinant, Belgium).

Detailed description

In a single-center, crossover study conducted at the University Hospital Zurich, Switzerland, 35 healthy, non-smoking adults (\>=18 years) will be invited to perform DLNO measurements in random order using the MasterScreenTM (PFT Pro, Jaeger, CareFusion, Hoechberg, Germany) and HypAir (Medisoft, Dinant, Belgium) devices during one study visit. The order of the tests on the MasterscreenTM and HypAir devices will be randomly allocated using central randomisation.

Conditions

• Healthy

Interventions

Type	Name	Description
DEVICE	Jaeger Masterscreen TM	Single-breath nitric oxide lung diffusing capacity
DEVICE	HypAir Medisoft	Single-breath nitric oxide lung diffusing capacity

Timeline

• Start date: 2019-10-01
• Primary completion: 2020-01-31
• Completion: 2020-01-31
• First posted: 2019-07-11
• Last updated: 2020-02-11

Locations

1 site across 1 country: Switzerland