NCT04016168

Idiopathic Pulmonary Fibrosis and Serum Bank

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 903 (actual)
• Sponsor: Rennes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Idiopathic pulmonary fibrosis (IPF) is the most common form of chronic idiopathic diffuse interstitial lung disease (DILD) in adults. It is a fibroproliferative, irreversible disease of unknown cause, usually progressive, occurring mainly from the age of 60 and limited to the lungs. IPF is a serious disease with a median survival rate at diagnosis of 3 years. The aim of the study is to set up a biocollection of serum from patients in a context of idiopathic DILD and a possible or confirmed diagnosis of common interstitial lung disease by chest CT. Patients will be recruited at the consultations of the Rennes Rare Lung Disease Competence Centre. These will be patients in stable condition or in acute exacerbation of IPF.

Detailed description

This study will initially focus on circulating serum CD163 markers, but a broader proteomics approach could be considered in a second phase to look for other markers of lung diseases.

Conditions

• Idiopathic Pulmonary Fibrosis
• Lung Diseases, Interstitial

Interventions

Type	Name	Description
BIOLOGICAL	Blood sample collection	Three additional blood tubes (3 x 8mL) will be collected for this study. They will be added to the traditional diagnostic assessment carried out for their IPF, during their consultation at the competence centre for rare lung diseases. These samples will be taken by a registered nurse in the presence and under the responsibility of the investigator.

Timeline

• Start date: 2014-10-22
• Primary completion: 2022-12-28
• Completion: 2022-12-28
• First posted: 2019-07-11
• Last updated: 2023-11-28

Locations

1 site across 1 country: France