Clinical Trials Directory

Trials / Completed

CompletedNCT04016077

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of PF-06651600 in Subjects With Hepatic Impairment and Healthy Volunteers

A PHASE 1, NON-RANDOMIZED, OPEN LABEL, MULTIPLE DOSE STUDY TO EVALUATE THE PHARMACOKINETICS, SAFETY AND TOLERABILITY OF PF 06651600 IN SUBJECTS WITH HEPATIC IMPAIRMENT AND IN HEALTHY SUBJECTS WITH NORMAL HEPATIC FUNCTION

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
18 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to characterize the effect of hepatic impairment on the pharmacokinetic(s) (PK) of PF-06651600 following administration of multiple once daily doses of PF-06651600. The safety and tolerability of PF-06651600 will also be evaluated in this study.

Conditions

Interventions

TypeNameDescription
DRUGPF-06651600 30 mgPF-06651600 in 10 mg oral tablets will be administered on days 1 to 10.

Timeline

Start date
2019-07-19
Primary completion
2020-03-05
Completion
2020-03-05
First posted
2019-07-11
Last updated
2021-04-08
Results posted
2021-04-08

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04016077. Inclusion in this directory is not an endorsement.