NCT04013841

Bowel Preparation Impact on the Intestinal Microbiome: Oral Preparation vs Enema

Bowel Preparation for Left Side Colon Surgery Impact on the Intestinal Microbiome: Oral Preparation vs Enema

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Vilnius University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Mechanical bowel preparation for left-sided colorectal surgery remains standard in most cases. However, there are some discrepancies on how to prepare the bowl, while rectal enema and oral agents are both available methods. The knowledge of intestinal microbiome role on surgical outcomes is increasing, since few recent reports linked microbiome composition to postoperative complications, such as anastomotic insufficiency. Although, it is not clear how the bowel preparation affects the gut microbiome. Therefore, different bowel preparation techniques impact on gut microbiome will be studied.

Conditions

• Colorectal Cancer

Interventions

Type	Name	Description
OTHER	Oral-agents/Enema	1. Oral-agents for mechanical bowel preparation prior to left-side colorectal resection 2. Enema for mechanical bowel preparation prior to left-side colorectal resection

Timeline

• Start date: 2021-04-08
• Primary completion: 2022-08-01
• Completion: 2023-11-01
• First posted: 2019-07-10
• Last updated: 2023-11-08

Locations

1 site across 1 country: Lithuania