NCT04012541

Comprehensive Oral Intervention in Patients With AMI

A Randomized Control Trial of Comprehensive Oral Intervention in Patients With Acute Myocardial Infarction: a Pilot Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 68 (estimated)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators performed a randomized controlled trial with investigator-masked design enrolling subjects with acute myocardial infarction. The purpose of this study is to find a treatment strategy to reduce the risk of recurrence of myocardial infarction through oral hygiene improvement.

Detailed description

Subjects were divided into a treatment group and a control group. Both sides receive basic periodontal examinations, but the treatment group receives active dental procedure such as scaling and root planing. Both groups also receive post-myocardial infarction management. As part of a pilot study, this study used the primary outcome measure for changes in surrogate markers rather than clinical outcomes.

Conditions

• Acute Myocardial Infarction
• Dental Diseases

Interventions

Type	Name	Description
PROCEDURE	active dental procedure	scaling and root planing
DRUG	post-myocardial infarction management	aspirin, clopidogrel, ticagrelor
RADIATION	basic periodontal examinations	panorama radiograph : full mouth periapical radiograph

Timeline

• Start date: 2019-07-05
• Primary completion: 2021-03-31
• Completion: 2021-03-31
• First posted: 2019-07-09
• Last updated: 2019-07-09

Locations

1 site across 1 country: South Korea