NCT04011956

Prognosis and Integrative Assessment of Aortic Coarctation Patients in China

Prognosis and Integrative Assessment of Aortic Coarctation Patients in CHINA

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Beijing Institute of Heart, Lung and Blood Vessel Diseases · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Not accepted

Summary

This is a systemic research of Chinese aortic coarctation patients, aiming to determine risk factors and serial biomarkers of aortic coarctation in prognosis.

Detailed description

The goal is to determine how much the left ventricle remodeling pre-operation and how it changes in the following-up duration after surgery, so does in the blood pressure and heart function. Risk factors associated with complications and prognosis are investigated and analyzed. Identification of novel biomarkers is needed to help predicting the prognosis, such as the left ventricle anti-remodeling, heart function and blood pressure improvement, as well as the exercise tolerance post-operation. The findings of this study will help the investigators developping new tests to monitor affected patients and optimize the operation as well as the follow-up procedure.

Conditions

• Coarctation of Aorta

Timeline

• Start date: 2019-03-01
• Primary completion: 2022-12-31
• Completion: 2023-12-31
• First posted: 2019-07-09
• Last updated: 2020-07-14

Locations

1 site across 1 country: China