NCT04005417

Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity

Bioavailable Stannous Fluoride Dentifrice Meta-Analyses: Effects on Dentine Hypersensitivity and Enamel Erosion

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,036 (actual)
• Sponsor: Procter and Gamble · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.

Conditions

• Dentine Hypersensitivity

Interventions

Type	Name	Description
DRUG	Stannous fluoride dentifrice	Stannous fluoride (0.454%) dentifrice
DRUG	Positive control dentifrice	Positive control dentifrice containing potassium nitrate or arginine.
DRUG	Negative control dentifrice	Negative control dentifrice containing either sodium fluoride (0.243%) or sodium monofluorophosphate (0.76%)

Timeline

• Start date: 2018-01-08
• Primary completion: 2018-11-30
• Completion: 2018-11-30
• First posted: 2019-07-02
• Last updated: 2019-07-02

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study