NCT04005092

Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema

Helmet Continuous Positive Airway Pressure Versus High Flow Nasal Cannula Oxygen in Acute Cardiogenic Pulmonary Oedema: A Randomized Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 188 (actual)
• Sponsor: Hospital Raja Permaisuri Bainun · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Oedema (ACPE) patients in the Emergency Department (ED) delivered by Helmet CPAP (hCPAP) and HFNC.Patients will be randomized to receive either hCPAP or HFNC.

Detailed description

Non-invasive ventilation(NIV) has different types of interfaces that had been used in acute hypoxaemic and hypercapnic respiratory failure. The appropriate interface is necessary to provide comfort and lead to the success of NIV. Helmet continuous positive airway pressure (hCPAP) is an NIV interface that allows the provision of high airway pressures with a minimal leak. HFNC which delivers heated humidified high flow oxygen provides a good alternative to the conventional NIV in terms of comfort

Conditions

• Cardiogenic Pulmonary Edema

Interventions

Type	Name	Description
DEVICE	hCPAP versus HFNC	The patient presented with Acute Cardiogenic Pulmonary Edema will be randomized into either helmet CPAP or HFNC.

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-08-31
• Completion: 2018-09-30
• First posted: 2019-07-02
• Last updated: 2021-01-22

Locations

1 site across 1 country: Malaysia