NCT04003116

Air Versus Oxygen for Intermediate-Risk Pulmonary Embolism (AIRE)

Randomized Clinical Trial to Evaluate the Efficacy and Safety of the Treatment With Supplementary Oxygen in Patients With Intermediate-Risk Pulmonary Embolism (PE)

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Ministry of Health, Spain · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective is to evaluate the efficacy of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism. The secondary objective is to evaluate the safety of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism.

Conditions

• Pulmonary Embolism

Interventions

Type	Name	Description
DRUG	Oxygen gas	Supplementary oxygen during the first 48 hours added to conventional anticoagulant treatment. Patients will receive anticoagulant treatment according to updated guidelines.

Timeline

• Start date: 2019-07-11
• Primary completion: 2022-04-24
• Completion: 2022-07-25
• First posted: 2019-07-01
• Last updated: 2022-08-18

Locations

7 sites across 1 country: Spain