NCT04001855

Evaluating the Effect of Bathing Additives in Atopic Dermatitis

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: University of Arizona · Academic / Other
• Sex: All
• Age: 5 Years
• Healthy volunteers: Not accepted

Summary

This proposed project will be an open-label, split-arm, randomized controlled pilot study. Up to 60 patients diagnosed with atopic dermatitis (eczema) will be enrolled in the study. The purpose of this study is to understand the change in skin barrier function and skin microbial composition in patients with atopic dermatitis following dilute bleach bath/soak and dilute vinegar bath/soak.

Detailed description

Atopic dermatitis (AD), also known as eczema, is an inflammatory skin condition that affects children and adults and causes skin redness, dryness and itching. Dilute bleach baths are standard of care for treatment of AD and work to decrease skin inflammation and modulate the skin microbiome. Dilute vinegar (acetic acid) has been reported to have similar effects on the skin. The purpose of this study is to evaluate the change in skin barrier function and skin microbial composition following baths or gauze soaks with dilute bleach and dilute vinegar.

Conditions

• Atopic Dermatitis
• Eczema

Interventions

Type	Name	Description
OTHER	Dilute vinegar (acetic acid)	Dilute vinegar baths or gauze soaks
OTHER	Dilute bleach	Dilute bleach baths or gauze soaks

Timeline

• Start date: 2019-07-01
• Primary completion: 2020-05-31
• Completion: 2020-05-31
• First posted: 2019-06-28
• Last updated: 2021-06-04

Locations

1 site across 1 country: United States