NCT03995433

EARLY-MYO-CMR-II Registry

EARLY-MYO-CMR-II (EARLY Assessment of MYOcardial Tissue Characteristics by CMR in NSTEMI) Registry

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: RenJi Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this registry is to depict the myocardial tissue characteristics in NSTEMI patients by CMR and other cardiac imaging modalities and to assess the prognostic value of imaging-derived indices. Information will be collected prospectively in about 2000 NSTEMI patients in 10 sites. Subjects will be followed for up to 5 years.

Detailed description

This is a prospective, multi-center, non-randomized, observational registry study of NSTEMI patients that undergo CMR examination. Information of other cardiac imagings and clinical outcomes are also prospectively collected in the database. This project will establish a prospective registry of 2000 NSTEMI patients in 10 sites with follow-ups of up to 5 years. The aim of the project will be as following: 1. To investigate myocardial pathological features and functional changes in NSTEMI patients. 2. To identify CMR-derived indices that are associated with adverse clinical outcomes. 3. To compare CMR with other alternative cardiac imaging modalities (i.e., echocardiography or SPECT) on prognostic prediction in NSTEMI patients. 4. To compare myocardial tissue characteristics and functional changes in STEMI (data derived from EARLY-MYO-CMR) and NSTEMI patients. 5. To verify GRACE Score classification in NSTEMI from CMR imaging view.

Conditions

• Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)

Timeline

• Start date: 2012-05-08
• Primary completion: 2019-07-08
• Completion: 2019-12-09
• First posted: 2019-06-24
• Last updated: 2019-06-24

Locations

1 site across 1 country: China