NCT03994575

North American Acute Coronary Syndrome (ACS) Reflective III Pilot

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 248 (actual)
• Sponsor: Canadian Heart Research Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The North American ACS Reflective III Pilot is an observational, Quality Enhancement Research Initiative (QuERI), knowledge translation program designed to give feedback to physicians on their post-ACS lipid-lowering management in an effort to support their decision-making and choice of therapies and thereby better achieve evidence-based, guideline-recommended management of post-ACS patients. The ACS Reflective III Pilot follows the completed ACS Registries I, II, and III, ACS Reflective I, and the ongoing ACS Reflective II programs.

Detailed description

The main objectives are: 1. To identify and describe post-ACS patients who do not achieve guideline-recommended LDL-C "target" (\<1.8 mmol/L in Canada, \>50% LDL-C lowering on high-intensity statin in the U.S.); 2. To identify opportunities where PCSK9 inhibitor therapy may be of potential benefit in the management of post-ACS patients to achieve guideline-recommended LDL-C goal by 1 year follow-up; and, 3. To determine reasons why physicians are not prescribing guideline-recommended LDL-C lowering therapies and/or patients are not achieving guideline-recommended LDL-C goals.

Conditions

• Dyslipidemias
• Acute Coronary Syndrome

Interventions

Type	Name	Description
OTHER	Guideline recommended feedback	The ACS Reflective III Pilot program is a quality assurance program where the decision to follow the recommendations and all treatment decisions related to patient care are left to the physician's discretion and feedback to the physician with their aggregate and individual patient data is intended as a quality assurance undertaking

Timeline

• Start date: 2019-03-15
• Primary completion: 2021-05-01
• Completion: 2021-05-30
• First posted: 2019-06-21
• Last updated: 2021-07-27

Locations

1 site across 1 country: Canada