NCT03994367

Animal and Plant Proteins and Glucose Metabolism

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Missouri-Columbia · Academic / Other
• Sex: All
• Age: 21 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The goal of this proposal is to determine the effect of a high protein diet in which the increase in protein intake is derived from different sources (animal vs plant and protein-rich whole foods vs protein isolates) on: i) liver and muscle insulin sensitivity; ii) the metabolic response to a meal, and iii) 24-h plasma concentration profiles of glucose, glucoregulatory hormones, and protein-derived metabolites purported to cause metabolic dysfunction.

Conditions

• Metabolic Syndrome
• Metabolic Syndrome, Protection Against
• Glucose Metabolism Disorders

Interventions

Type	Name	Description
OTHER	High animal protein isolate	Increased dietary protein content from animal protein isolates
OTHER	High animal protein whole food	Increased dietary protein content from animal protein whole food
OTHER	High plant protein isolate	Increased dietary protein content from plant protein isolates
OTHER	High plant protein whole food	Increased dietary protein content from animal protein whole food

Timeline

• Start date: 2019-07-12
• Primary completion: 2028-02-25
• Completion: 2028-04-25
• First posted: 2019-06-21
• Last updated: 2025-03-17

Locations

1 site across 1 country: United States