NCT03992183

Utility of CAML as Diagnostic for Early Stage Lung Cancer

TH-146: Cancer Associated Macrophage-Like (CAML) Cells to Enhance Detection of Early Stage Lung Cancer

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: Fox Chase Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Primary Objective Determine the prevalence of CAMLS in patients with pulmonary nodules. Secondary Objectives Determine the positive and negative predictive value of CAMLS in patients with pulmonary nodules who undergo biopsy. Model combinations of clinical factors with the presence/absence of CAMLS to refine strategies for assessment of patients with pulmonary nodules. Evaluate whether these measures result in enhanced T-cell activity and/or NK cell function and number

Conditions

• Pulmonary Nodule, Multiple
• Pulmonary Nodule, Solitary

Timeline

• Start date: 2019-05-21
• Primary completion: 2022-11-14
• Completion: 2022-11-14
• First posted: 2019-06-20
• Last updated: 2026-03-04

Locations

2 sites across 1 country: United States