NCT03990831

Frontal Lobe Oxyhemoglobin Levels in Patients With Lower Extremity Burns Assessed Using a fNIRS

Frontal Lobe Oxyhemoglobin Levels in Patients With Lower Extremity Burns Assessed Using a Functional Near-Infrared Spectroscopy Device During Usual Walking: A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Hangang Sacred Heart Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Investigators investigate the patterns of cortical activation using the NIRST in patients with peripheral neurological injury caused by lower extremity burns.

Detailed description

Understanding the mechanisms associated with locomotor networks may be of benefit for rehabilitation of burn victims with neurological locomotor deficits. However, the effects of peripheral neurological injury on locomotor network remains unknown. A wearable functional near-infrared spectroscopy (fNIRS) device has been developed for studying cortical hemodynamics. Changes in cortical activity has not previously been documented in patients with burn injury. Investigators assessed 15 patients with lower extremity burns and 11 healthy controls. Investigators measured walking-related cortical activity using an fNIRS device at baseline and during usual walking. Cortical activity was measured by evaluating relative changes in oxyhemoglobin level. The NIRST Analysis Tool v2.1 was utilized to analyze fNIRS data in a MATLAB environment.

Conditions

• Walking

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Functional near-infrared spectroscopy (fNIRS)	Functional near-infrared spectroscopy (fNIRS) measurement

Timeline

• Start date: 2019-07-09
• Primary completion: 2019-07-09
• Completion: 2019-07-09
• First posted: 2019-06-19
• Last updated: 2019-07-10

Locations

1 site across 1 country: South Korea