NCT03989960

Modified Intubation-surfactant-extubation (InSurE) Technique in Preterm Neonates With Respiratory Distress Syndrome

Application of Modified Intubation-surfactant-extubation (InSurE) Technique in Preterm Neonates With Respiratory Distress Syndrome

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: The First Affiliated Hospital with Nanjing Medical University · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

This study evaluates the less invasive surfactant administration (LISA) combined with synchronized nasal intermittent positive pressure ventilation (SNIPPV) technique in the treatment of respiratory distress syndrome (RDS) of preterm neonates. The modified InSurE group will receive "LISA + SNIPPV" technique, while the traditional InSurE group will receive the intubation, surfactant, extubation and CPAP technique.

Conditions

• Respiratory Distress Syndrome of Newborn

Interventions

Type	Name	Description
PROCEDURE	LISA+SNIPPV	The LISA+SNIPPV group receives PS by the way of invasive surfactant administration technique and selects nasal synchronized intermittent positive pressure ventilation.
PROCEDURE	traditional InSurE	The traditional InSurE group receives intubation-surfactant- extubation technique and selects CPAP ventilation.

Timeline

• Start date: 2018-08-01
• Primary completion: 2019-12-31
• Completion: 2019-12-31
• First posted: 2019-06-18
• Last updated: 2019-06-21

Locations

1 site across 1 country: China