Trials / Unknown
UnknownNCT03989700
Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs
Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs: Randomized Controlled Trial
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Mahidol University · Academic / Other
- Sex
- All
- Age
- 1 Month – 15 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine effect of thiamin supplementation on thiamin status by measuring thiamin pyrophosphate effect in children with heart disease receiving diuretic drugs.
Detailed description
Children with heart disease receiving diuretic drugs are susceptible to thiamin deficiency due to increase renal loss. Thiamin deficiency causes abnormal cardiac contraction resulting in heart failure.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Thiamine Mononitrate | Low dose group: thaimine mononitrate 25 mg/day per oral daily for 4 weeks High dose group: thaimine mononitrate 50 mg/day per oral daily for 4 weeks Placebo group: placebo 25 mg/day per oral daily for 4 weeks |
Timeline
- Start date
- 2019-07-01
- Primary completion
- 2020-06-30
- Completion
- 2020-07-31
- First posted
- 2019-06-18
- Last updated
- 2019-06-20
Locations
1 site across 1 country: Thailand
Source: ClinicalTrials.gov record NCT03989700. Inclusion in this directory is not an endorsement.