Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT03989414

A Study to Determine the Recommended Dose and Regimen and to Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)

A Phase 1/2, Multicenter, Open-label, Study to Determine the Recommended Dose and Regimen, and Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)

Status
Active Not Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
424 (estimated)
Sponsor
Celgene · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety and preliminary efficacy of CC-92480 in combination with standard treatments.

Conditions

Interventions

TypeNameDescription
DRUGCC-92480Specified dose on specified days
DRUGBortezomibSpecified dose on specified days
DRUGDexamethasoneSpecified dose on specified days
DRUGDaratumumabSpecified dose on specified days
DRUGCarfilzomibSpecified dose on specified days
DRUGElotuzumabSpecified dose on specified days
DRUGIsatuximabSpecified dose on specified days
DRUGCarfilzomibSpecified dose on specified days

Timeline

Start date
2019-09-30
Primary completion
2026-11-30
Completion
2026-11-30
First posted
2019-06-18
Last updated
2024-11-29

Locations

49 sites across 9 countries: United States, Canada, Czechia, Denmark, France, Germany, Greece, Italy, Spain

Regulatory

Source: ClinicalTrials.gov record NCT03989414. Inclusion in this directory is not an endorsement.