NCT03988075

Non-opioid Based Pain Control After Thyroidectomy

Use of Enhanced Recovery After Surgery (ERAS) in Minimizing Opioid Use for Patients Undergoing Thyroidectomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Medstar Health Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Pain control modalities were evaluated after thyroidectomy.

Detailed description

Pain control modalities were evaluated after thyroidectomy. Patients were randomized to one of two pain control regimens. The control group received conventional opioid based post operative analgesia while the test group received an enhanced recovery after surgery (ERAS) based anesthesia with use of acetaminophen and non-steroidal anti-inflammatory drugs for the post operative period with opioid medications available for break through pain only. Pain scores (measured on visual analog scale) and opioid use (measured in morphine equivalent dose) were measured after completion of the operation.

Conditions

• Pain
• Thyroidectomy

Interventions

Type	Name	Description
OTHER	Acetaminophen and hydrocodone based pain control	Patients receive acetaminophen 650mg every 4 for pain level 1-3, hydrocodone/acetaminophen 5/325mg every 4 for pain level 4-6, or hydrocodone/acetaminophen 10/650mg every 4 for pain level 7-10 on as needed basis.
OTHER	Acetaminophen and ibuprofen based pain control	Patients receive standing dose of acetaminophen 650mg every 8 hours and ibuprofen 800mg every 8 hours with alternating ibuprofen and acetaminophen every 4 hours.

Timeline

• Start date: 2018-07-24
• Primary completion: 2019-08-01
• Completion: 2019-09-30
• First posted: 2019-06-17
• Last updated: 2020-05-12

Locations

1 site across 1 country: United States