NCT03985826

Health Care Utilisation Among Survivors of Childhood Acute Lymphoblastic Leukaemia

Health Care Utilisation Following Childhood Acute Lymphoblastic Leukaemia: A Matched Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 7,348 (actual)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: —

Summary

Improved understanding of the long-time healthcare utilisation of childhood cancer survivors is relevant as it can be seen as a proxy for the population's morbidity. The investigators will conduct a historic population-based matched cohort study using Danish nationwide registry data. Eligible children are children 1.0-17.9 years diagnosed with Acute lymphoblastic leukaemia (ALL) in Denmark from 1994 till 2016. The primary outcome is yearly contact rates to primary healthcare.

Detailed description

Acute lymphoblastic leukaemia (ALL) is the most frequent single form of cancer in children accounting for 40-45 new cases every year in Denmark. Over the past decades, advances in treatment have led to an increasing number of children who survive cancer and more than 80% of children with ALL now become long-term survivors. This means a growing population of childhood ALL survivors. In survivors, the cancer itself and treatment late-effects can lead to ongoing health care use. Register studies of long-term survivors of childhood cancer have shown an increased risk of hospitalisation compared to the general population. It is mentioned in many of the studies that contact rates could be underestimated when looking at hospital contacts only. The literature about non-hospital-based contacts with a doctor in childhood cancer survivors is scarce.

Conditions

• Precursor Cell Lymphoblastic Leukemia-Lymphoma

Interventions

Type	Name	Description
OTHER	Diagnosis of and treatment for Acute lymphoblastic leukaemia in childhood	The cohort of ALL survivors has all been diagnosed and treated for ALL in childhood

Timeline

• Start date: 2019-09-01
• Primary completion: 2019-11-30
• Completion: 2019-11-30
• First posted: 2019-06-14
• Last updated: 2020-12-03

Locations

1 site across 1 country: Denmark