NCT03985540

Treating Cognitive Deficits in Traumatic Spinal Cord Injury (SCI)

Treating Cognitive Deficits in Traumatic Spinal Cord Injury (SCI): A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (estimated)
• Sponsor: Kessler Foundation · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to investigate the effectiveness of a memory retraining program and a processing speed program in a spinal cord injured (SCI) population. The study is designed to research how well different types of techniques can help people with SCI improve in areas where they might have difficulties such as memory or processing speed, (time it takes to process information provided).

Detailed description

The objectives of the currently proposed randomized clinical trial are to (1) apply a treatment protocol for Processing Speed and Learning and memory impairments, well-validated in other neurological populations, to individuals with SCI with objectively observable deficits in these areas and document efficacy on standard neuropsychological testing; (2) assess the effectiveness of the interventions in persons with SCI utilizing global measures of everyday life; (3) evaluate the long-term benefit of treatment. Prior to enrollment in the study protocol, all potential subjects will undergo a 2-part screening: (1) an initial screening examination via telephone during which basic information will be gathered and (2) a detailed, in-person screening that will be completed on if the subject passes the initial screen. Individuals must meet full screening criteria to be eligible for participation.

Conditions

• Spinal Cord Injuries

Interventions

Type	Name	Description
BEHAVIORAL	Behavorial; memory exercise	Memory training twice a week for 5 weeks.
BEHAVIORAL	Placebo; memory exercise	Placebo Memory training twice a week for 5 weeks
BEHAVIORAL	Behavioral: speed exercises	Speed training twice a week for 5 weeks.
BEHAVIORAL	Placebo speed training	Placebo Speed training twice a week for 5 weeks.

Timeline

• Start date: 2016-11-16
• Primary completion: 2022-10-30
• Completion: 2022-11-14
• First posted: 2019-06-13
• Last updated: 2023-01-18

Locations

1 site across 1 country: United States