Trials / Unknown
UnknownNCT03983902
Placental Transfusion Methods and Stem Cells
The Effect of Placental Transfusion Methods on the Potentially Transfusion Levels of Endothelial Progenitor Cell and CD34+ Hematopoietic Stem Cell
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 96 (estimated)
- Sponsor
- Ankara University · Academic / Other
- Sex
- All
- Age
- 3 Minutes
- Healthy volunteers
- Not accepted
Summary
To measure the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells levels, and placental residual volume by delayed cord clamping, umbilical cord milking or immediate cord clamping in newborns at different gestational weeks.
Detailed description
Umbilical cord blood is a rich source of stem cells. Placental transfusion is the transfer of the placental blood to the baby until the cord clamped during the birth. Placental transfusion can be accomplished by delayed cord clamping or umbilical cord milking. One group will receive 2 minutes of delayed cord clamping, the second group will receive umbilical cord milking and the third group will receive immediate cord clamping. Following the cord clamping, the blood samples will be taken from the placental site of the umbilical cord to measure the stem cells from all subjects and placental residual volume will be measured. Delivery room conditions, hospitalization (if needed), short-term outcome during hospitalization, prematurity related morbidities (if baby is preterm) will be recorded.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Delayed cord clamping | Delayed cord clamping will occur for up to 2 minutes. |
| PROCEDURE | Umbilical cord milking | Umbilical cord milking will occur milking of the 30 cm of the cord from placental site to baby, at a speed of 5 cm/second, 3 times in preterm newborns, 4 times in term newborns. |
| PROCEDURE | Immediate cord clamping | Immediate cord clamping will occur in 20 seconds after birth. |
Timeline
- Start date
- 2019-07-01
- Primary completion
- 2020-12-31
- Completion
- 2021-06-30
- First posted
- 2019-06-12
- Last updated
- 2019-06-14
Source: ClinicalTrials.gov record NCT03983902. Inclusion in this directory is not an endorsement.