NCT03978169

Pulmonary Impacts of Anaesthetic Modalities Evaluated by Ultrasound

Pulmonary Impacts of Anaesthetic Modalities Evaluated by Ultrasound: A Prospective Study in Scheduled Knee Arthroplasty

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 99 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A prospective, observational, monocentric study aimed at identifying ultrasound changes in anaesthesia on the pulmonary parenchyma after knee arthroplastic surgery using the LUS score in the preoperative, immediate post-operative (D0) and late post-operative (D1) periods.

Detailed description

Post-operative pulmonary complications are responsible from morbidity and mortality close to cardiovascular complications. Perioperative and post-operative respiratory changes are secondary to anaesthesia (general anaesthesia, elongated position, tidal volume) and to surgery in particular abdominal and cardiothoracic surgery. Several risk factors related to patients were identified: age, ASA score\> 2, functional dependence, chronic obstructive pulmonary disease, congestive heart failure, obesity, smoking. Pulmonary ultrasound is a simple and rapid means of monitoring, widely used in resuscitation and developing in anaesthesia. The hypothesis of the study is that anaesthesia and / or ventilation is responsible for lung lesions observable by ultrasound from the recovery room, even after extra-thoracic surgeries. To do this, it will perform 3 pleuro-pulmonary ultrasound scans, preoperatively on the day of surgery, post-operatively in the recovery room and the day after surgery. LUS score will be calculated. Preoperative data (morphology, comorbidities), preoperative (ventilation, filling, position, type of anaesthesia - general anaesthesia with intubation or laryngeal mask, spinal anaesthesia- , type of surgery) and postoperative data (constants, oxygen therapy, complications) will be collected.

Conditions

• Anesthesia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	pleuropulmonary ultrasound	three pleuro-pulmonary ultrasound scans will be performed, preoperatively on the day of surgery, post-operatively in the recovery room and the day after surgery

Timeline

• Start date: 2018-12-13
• Primary completion: 2020-11-01
• Completion: 2020-11-01
• First posted: 2019-06-07
• Last updated: 2019-06-07

Locations

1 site across 1 country: France