NCT03976960

Clinical and Biological Database in Colon Cancer and Colic Tumors

Prospective, Multicenter, Clinical and Biological Database Set-up in Colon Cancer and Colic Tumors

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 600 (estimated)
• Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Developement of a clinical and biological database in colon cancer and colic tumors in order to better understand tumor invasion and metastatic scattering processes. The investigators hope that a better understanding of tumoral invasion process will lead to the discovery of new biomarkers and new drugs.

Detailed description

As the second leading cause of cancer-related death in France, colorectal cancer is a major public health problem. Each year, 37 000 cases are newly diagnosed in France and 17 000 patients die of the disease. Colorectal cancer is due to molecular and genetic damages involved in all tumorigenesis steps, transition from healthy tissue to adenoma and finally to invasive carcinoma stage. The investigators hope that a to better understand tumor invasion and metastatic scattering processes will allow therapeutic innovation and the emergence of new biomarkers. However, the study of early tumorigenesis phases as well as advanced stages of the disease is currently limited due to a lack of tissue samples. In this context, the Montpellier Cancer Institute (ICM) decided to initiate a biological collection dedicated to the tissular and blood samples of patients with colorectal cancer.

Conditions

• Cancer Colon

Interventions

Type	Name	Description
OTHER	Biological collection	The biological collection will also include samples of blood samples collected before or after surgery but also samples frozen and/or paraffin-embedded tissue sections.

Timeline

• Start date: 2018-09-19
• Primary completion: 2025-12-01
• Completion: 2030-12-01
• First posted: 2019-06-06
• Last updated: 2025-02-12

Locations

2 sites across 1 country: France