NCT03976206

Very Small Embryonic-like Stem Cells for Facial Skin Antiaging

Autologous Very Small Embryonic-like Stem Cells(VSELs) for Facial Skin Antiaging

• Status: Withdrawn
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Fuda Cancer Hospital, Guangzhou · Academic / Other
• Sex: All
• Age: 40 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is the safety and efficacy of autologous very small embryonic-like stem cells(VSELs) to facial skin antiaging.

Detailed description

VSELs come from the patient's peripheral blood, and will be injected in left preauricular area, followed by skin pathology to compare the improvement of skin aging. Two 0.5 × 1 cm fragments of skin and subcutaneous tissue was removed from bilateral preauricular areas for morphologic analysis by optical and electron microscopy. Histologic analysis of skin biopsy specimens was performed by hematoxylin and eosin, picrosirius red (for visualization of collagen), and orcein (for visualization of elastic fibers) staining.

Conditions

• Stem Cell Transplant Complications
• Skin Inflammation

Interventions

Type	Name	Description
BIOLOGICAL	Very small embryonic-like stem cell	We carried out the subdermal application of VSELs with a 1-mL syringe (volume, 0.4 mL) coupled to a 30-gauge needle, in the left preauricular area (1-cm2 area), 2 cm distal from the tragus

Timeline

• Start date: 2019-07-06
• Primary completion: 2020-05-20
• Completion: 2020-07-01
• First posted: 2019-06-05
• Last updated: 2020-10-19

Locations

1 site across 1 country: China