NCT03973619

Urethral Stricture: A Comparison Between Jugal or Labial Graft Urethroplasty

Urethral Stricture Repair: A Prospective Randomized Analysis Between Jugal or Labial Graft in Buccal Mucosa Urethroplasty

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 77 (actual)
• Sponsor: Hospital de Clinicas de Porto Alegre · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

Buccal mucosa urethroplasty is a current fashion in urethral stricture management. In our university centre (Hospital de Clínicas de Porto Alegre) is a common surgical treatment choice. This paper aims to evaluate the success rate of this treatment after randomized choice between labial and jugal (inner cheek) grafts during the past two years.

Detailed description

Free dorsal graft urethroplasty, first described by Barbagli et al, has been shown better results than ventral grafts. Fixed grafts on the corpora cavernosa results in a better mechanical support and vascular supply, with less chance to complications such as pseudodiverticula and sacculations either a better urethral phisiology. This study aims to evaluate the current surgical management in our centre: buccal mucosa graft urethroplasty with jugal or labial replacement, comparing their group success rate and complications between the groups in patients led to surgery from October 2016 to June 2018. Prospective analysis from urethral stricture surgical HCPA patient data by dorsal buccal mucosa graft urethroplasty. The graft choice were done by a software. Longer stricture with transoperative need for the two grafts use were excluded. Success rate were measured with a no stricture de novo or absence of complications in a six month interval.

Conditions

• Urethral Stricture

Interventions

Type	Name	Description
PROCEDURE	Labial Graft	As replacement of the damaged urethral tissue, we used a buccal mucosa graft (labial graft).
PROCEDURE	Jugal Graft	As replacement of the damaged urethral tissue, we used a buccal mucosa graft(inner cheek - jugal graft).

Timeline

• Start date: 2016-10-01
• Primary completion: 2018-07-31
• Completion: 2018-11-27
• First posted: 2019-06-04
• Last updated: 2020-08-24