NCT03972813

Optimizing HPV Vaccine Introduction in Shanghai, China

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,021 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Within low, middle, and upper income countries, low vaccine coverage results from both obstacles to vaccine access and low confidence in vaccine programs. Thus, it is critical to determine how best to enhance trust in vaccines as increasing numbers of vaccines are recommended for use. Even though the context accompanying the initial roll-out of a vaccine can have a large impact on people's perceptions of the vaccine and the corresponding disease, it is not clear how to best introduce a vaccine to increase public confidence and enhance uptake. The US roll-out of the human papillomavirus (HPV) vaccine framed HPV as a sexually transmitted infection, which proved to be an impediment to efforts to increase vaccine uptake \>10 years after its introduction. This study will use an educational experiment, where parents of children will be exposed to information about the HPV vaccination in different ways. Parents will be introduced to the HPV vaccine through different scenarios with varying emphases (i.e., age at vaccination, types of transmission, type of cancer prevention). The aim will be to determine how the framing of the HPV vaccination across several dimensions affects short-term willingness to receive it.

Conditions

• Vaccine Refusal

Interventions

Type	Name	Description
BEHAVIORAL	Broadened information about cancers	Caregivers receive information that HPV causes more than just cervical cancer.
BEHAVIORAL	Information about STDs	Caregivers learn that HPV is an STD.
BEHAVIORAL	Information about infectious disease	Caregivers learn that HPV is infectious (but information that it is an STD is omitted).
BEHAVIORAL	Recommendation for children 12 years old	Caregivers are prompted to get their child vaccinated when the child is 12 years old.
BEHAVIORAL	Recommendation for children 18 years old	Caregivers are prompted to get their child vaccinated when the child is 18 years old.
BEHAVIORAL	Standard age information	Caregivers are given information about when the HPV vaccination can be given in China, but no additional recommendations.
BEHAVIORAL	Cervical cancer	Caregivers are told that HPV causes cervical cancer.
BEHAVIORAL	Blank information about communicability	Caregivers are not given any information on how HPV is spread.

Timeline

• Start date: 2019-05-28
• Primary completion: 2019-08-31
• Completion: 2019-08-31
• First posted: 2019-06-04
• Last updated: 2025-01-15
• Results posted: 2020-01-13

Locations

1 site across 1 country: China