Clinical Trials Directory

Trials / Completed

CompletedNCT03972280

Safety and Pharmacokinetics of Repeat Doses of CSL324 in Subjects With Hidradenitis Suppurativa and Palmoplantar Pustulosis

A Multicenter, Open-label, 2-regimen, Repeat-dose Study to Assess the Safety and Pharmacokinetics of Intravenous CSL324 in Subjects With Hidradenitis Suppurativa and Palmoplantar Pustulosis

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
39 (actual)
Sponsor
CSL Behring · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Study CSL324\_1002 will investigate the safety and pharmacokinetics of repeat doses of CSL324 in subjects with hidradenitis suppurativa and palmoplantar pustulosis. CSL324 is a novel, recombinant therapy that may treat diseases caused by increased numbers of neutrophils at sites of inflammation.

Conditions

Interventions

TypeNameDescription
BIOLOGICALRecombinant anti-granulocyte colony-stimulating factor (G-CSF) receptor monoclonal antibodyRecombinant anti-G-CSF receptor monoclonal antibody is a preservative-free, sterile liquid formulation that is suitable for intravenous infusion

Timeline

Start date
2019-07-04
Primary completion
2022-10-04
Completion
2022-10-04
First posted
2019-06-03
Last updated
2023-05-26

Locations

11 sites across 3 countries: Australia, Denmark, Germany

Source: ClinicalTrials.gov record NCT03972280. Inclusion in this directory is not an endorsement.