Clinical Trials Directory

Trials / Unknown

UnknownNCT03971747

AFP Specific T Cell Receptor Transduced T Cells Injection(C-TCR055) in Unresectable Hepatocellular Carcinoma

A Phase 1 Study of AFP Specific T Cell Receptor Transduced T Cells Injection in Unresectable Hepatocellular Carcinoma

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
9 (estimated)
Sponsor
Shanghai AbelZeta Ltd. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

A phase 1 study that aimed to assess the safety and anti-tumor activity of C-TCR055 injection in unresectable HCC patients.

Detailed description

This study plans to enroll 9 patients to assess the safety of C-TCR055. Subjects who meet the eligibility criteria will receive a single dose of C-TCR055 injection, and will be followed up post treatment for safety monitoring. The follow up period will last 12 months.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAFP Specific T Cell Receptor T CellsAutologous T cells transduced with lentivirus encoding AFP specific TCR gene

Timeline

Start date
2019-08-06
Primary completion
2020-06-01
Completion
2021-04-01
First posted
2019-06-03
Last updated
2020-04-07

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT03971747. Inclusion in this directory is not an endorsement.