NCT03967470

Bacteriotherapy to Improve Underarm Odor

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 67 (actual)
• Sponsor: University Ghent · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The goal is to improve the underarm odor by changing the microbiome. The autochthonous bacterial community is replaced by a non-smelling microbiome, by daily application of bacteria in a spray.

Detailed description

Participants are recruited and selected based on their initial underarm odor and underarm microbiome. The participants use two sprays: one spray containing the bacteria, and the other nothing (placebo). Participants do not know which spray they have. They use one spray during one month, and meanwhile take samples of their underarm microbiome (for sequencing), volatome (for GC/MS analysis) and odor (for odor panel analysis). Samples are stored in the freezer and brought to the university after one month, when they receive the second spray. The bacterial spray contains bacteria that are correlated with good underarm odor.

Conditions

• Bromhidrosis

Interventions

Type	Name	Description
BIOLOGICAL	Bacterial spray	Bacterial spray containing bacteria that do not cause underarm malodor

Timeline

• Start date: 2018-10-01
• Primary completion: 2022-12-30
• Completion: 2022-12-30
• First posted: 2019-05-30
• Last updated: 2023-12-15

Locations

1 site across 1 country: Belgium