NCT03966339

Growth Hormone Adding to Controlled Ovarian Hyperstimulation for Improving Embryo Quality

Growth Hormone Adding to Controlled Ovarian Hyperstimulation for Improving Embryo Quality：a Randomized Controlled Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 128 (estimated)
• Sponsor: Reproductive & Genetic Hospital of CITIC-Xiangya · Academic / Other
• Sex: Female
• Age: 20 Years – 39 Years
• Healthy volunteers: Not accepted

Summary

GH plays an important role in the synthesis of ovarian steroid hormone and follicular development as a paracrine hormone.GH can regulate the growth hormone receptor and strengthen the function of mitochondria to improve the quality of the female oocyte.In this study, a prospective randomized control was used to explore the effect of GH adjuvant therapy on embryo quality.

Conditions

• Infertility,Female

Interventions

Type	Name	Description
DRUG	Growth hormone	GH has been considered as a cogonadotropin, which plays an important role in the synthesis of ovarian steroid hormone and follicular development as a paracrine hormone.GH can regulate the growth hormone receptor and strengthen the function of mitochondria to improve the quality of the female oocyte.

Timeline

• Start date: 2019-08-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2019-05-29
• Last updated: 2022-01-11

Locations

1 site across 1 country: China