NCT03965442

Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome

Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome: a Cross-sectional Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 66 (estimated)
• Sponsor: Hospital de Base · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Chronic postoperative pain is an entity that is usually neglected by anesthetists, but several studies show that the choice of anesthetic technique may interfere with this prevalence. Esmolol is a selective beta-blocker of ultra fast duration that has been studied as a perioperative venous adjuvant with antihyperalgesic and opioid sparing action. The investigators ventured the possibility of this anti-hyperalgesic effect attenuating the chronic pain syndrome post-mastectomy.

Conditions

• Post-mastectomy Pain Syndrome

Interventions

Type	Name	Description
DRUG	Control	Patients who underwent mastectomy under standard general anesthesia
DRUG	Esmolol	Patients who underwent mastectomy under general anesthesia with esmolol infusion

Timeline

• Start date: 2019-01-01
• Primary completion: 2019-07-31
• Completion: 2019-07-31
• First posted: 2019-05-29
• Last updated: 2019-05-29

Locations

1 site across 1 country: Brazil

Regulatory

• FDA-regulated drug study