Trials / Completed
CompletedNCT03964948
Kidney Fibrosis and MRI
Development of Novel MRI Methods for Detecting and Measuring Renal Injury/Fibrosis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 37 (actual)
- Sponsor
- Children's Hospital Medical Center, Cincinnati · Academic / Other
- Sex
- All
- Age
- 10 Years – 25 Years
- Healthy volunteers
- Accepted
Summary
The investigators plan a prospective cross-sectional study of pediatric and adult healthy volunteers and patients with chronic kidney disease that will correlate a variety of quantitative MRI biomarkers with severity of renal insufficiency and available histopathology. Over 3 years, the investigators will recruit approximately 20 healthy volunteers, 20 patients with chronic kidney disease (CKD) Stage 2-5, and 20 patients with renal transplant kidneys. The investigators also plan to assess the effect of inflammation on the quantitative MRI biomarkers by recruiting approximately 20 additional patients with active lupus nephritis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Kidney MRI | An MRI examination will be completed per research MRI protocol. |
Timeline
- Start date
- 2018-08-06
- Primary completion
- 2021-06-18
- Completion
- 2021-06-18
- First posted
- 2019-05-28
- Last updated
- 2021-09-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03964948. Inclusion in this directory is not an endorsement.