Clinical Trials Directory

Trials / Completed

CompletedNCT03964493

TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection

Phase 2, Double-Blind, Randomized, Multicenter, Parallel, Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection in Adults

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
120 (actual)
Sponsor
TenNor Therapeutics Limited · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate safety, tolerability, pharmacokinetic characteristics and efficacy of TNP-2092 in adults with ABSSSI suspected or confirmed to be caused by gram-positive pathogens.

Detailed description

This Phase 2, double-blind, randomized, multicenter, parallel, controlled study is conducted to evaluate safety, tolerability, pharmacokinetics and efficacy of TNP-2092, and vancomycin in adults with ABSSSI suspected or confirmed to be caused by gram-positive pathogens. The duration of the treatment period is a minimum of 7 days and a maximum of 14 days.

Conditions

Interventions

TypeNameDescription
DRUGTNP-2092TNP-2092 100mg/vial
DRUGVancomycinVancomycin 1g/vial

Timeline

Start date
2019-04-20
Primary completion
2020-09-28
Completion
2020-09-28
First posted
2019-05-28
Last updated
2023-12-01
Results posted
2023-12-01

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03964493. Inclusion in this directory is not an endorsement.