Clinical Trials Directory

Trials / Completed

CompletedNCT03963596

Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Myopia

Collaborative Ocular Antiangiogenic Study of Ukraine. Multicentral, Open-label, Randomized, Prospective Study of Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Myopia

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
122 (actual)
Sponsor
The Filatov Institute of Eye Diseases and Tissue Therapy · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the effectiveness of antiangiogenic therapy to choroidal neovascularization secondary to pathologic myopia.

Detailed description

The purpose of this study is to determine the effectiveness of antiangiogenic therapy to choroidal neovascularization secondary to pathologic myopia. This study is planned as a follow-up. Patients with myopia included in it will receive antiangiogenic therapy in accordance with the approved indications for use indicated in the instructions for the use of drugs in Ukraine. The treatment proposed in this study is based on the world experience and scientific developments of the Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine ". Therefore, it is expected that the benefit / risk ratio in relation to the participation in this study should not be different from that described in the scientific literature and the benefits outweigh the risk. It is known that the absence of treatment in these diseases leads to an irreparable loss of central vision. Patients with a pathologic myopia with CNV (native) will be treated with antiangiogenic drugs according to the regimen pro re nata.

Conditions

Interventions

TypeNameDescription
PROCEDUREIntravitreal injectionIntravitreal injection to the regimen pro re nata.

Timeline

Start date
2018-03-27
Primary completion
2020-07-01
Completion
2020-12-31
First posted
2019-05-24
Last updated
2023-01-25

Locations

3 sites across 1 country: Ukraine

Source: ClinicalTrials.gov record NCT03963596. Inclusion in this directory is not an endorsement.